Dr. Pimple Popper: Before The Pop Season 2 is yet to be announced by TLC

Luke has hundreds of lumps on his body that he has been hiding from his in-laws for over nine years. A trio of skin conditions cause Tanisha tremendous stress. John has been avoiding family gatherings since being teased about the huge lump on his neck.

After being sucker-punched, Dexter developed a large mass that protrudes from his jaw. Zaria hopes her son might avoid the multitude of tiny face bumps that seem to run in her family. Tracie and Stacie are twins with matching head bumps.

Musician Kayla has itchy eczema everywhere, making it difficult to play her guitar. Juan was bullied so badly over the painful bumps he has on his neck and torso that he dropped out of high school. Teresa has a mysterious, deflating arm growth.

Shakisaha's earlobe split in half during a failed body modification attempt. After recovering from a flesh-eating disease, Kelly Ann developed a huge leg growth. Terrified of doctors, Dennis has gone 30 years without seeking treatment for his head bumps!

Roger's case of rhinophyma is so extreme that he has difficulty breathing. The small, evenly spaced bumps all over Natalie's body are interfering with her life. Virginia thinks the equally sized lumps on her arms make her look like a football player.

Audrey has a severe condition that leaves her with painful bumps on every inch of her body. An embarrassing armpit growth affects former marine Matt's self-esteem. Jaclyn has a lemon-sized bump on the back of her head.

Larry has a hanging thigh growth so large that the weight of it makes his leg go numb. Cheerleader Bailee has a disappearing back bump she has named Ralph. With three complicated skin conditions, Ashley's case is considered a "skin nightmare."

Fun-loving Che'Re has a squishy, dark bump on her cheek that has left her depressed and self-conscious. Buck has been breaking out in painful, fluid-filled blisters for three years. Telly developed a massive bump behind his head after being hit by a car.

Reginald hides the embarrassing growths on the back of his head with knitted hats. Jackie has lived with her huge shoulder lump for nine years. Leonardo has a chilling-looking growth on his head, but the thought of surgery terrifies him.

Due to the global pandemic, Dr. Lee has started consulting with her patients through video chat. Monica's big, bumpy birthmark is taking over her neck. Shane has a firm bump precariously near his eye. Ellie's psoriasis is so severe that it clogs her ears.